Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.
BACKGROUND: Leishmania (L.) species are the causative agent of leishmaniasis.Due to the lack of efficient vaccine candidates, drug therapies are the only option to deal with Test Boards cutaneous leishmaniasis.Unfortunately, chemotherapeutic interventions show high toxicity in addition to an increased risk of dissemination of drug-resistant parasit